Mohammad Hossein Jarahzadeh, Banafshe Fuladgar, Mohammad Reza Mirjalili, Farshid Rahimi- Bashar, Mohammad Hossein Dehghani, Kazem Barzegar
"This study investigated the local effect of Dexamethasone on sore throat after surgery using the LMA. This study is a double-blind randomized clinical trial conducted on 100 patients underwent general anesthesia who were candidates of placement of laryngeal mask airway. The patients were randomly assigned to two groups of 50. In the experimental group, Dexamethasone was applied to the cuff of the LMA and in the control group; distilled water was applied to the cuff. The rate of incidence and intensity of sore throat, prevalence of coughing, and hoarseness were assessed at 1, 2, and 24 hours after surgery. Data were analysed by t-test, Chi-Square test, and Fisher’s Exact test. The incidence of sore throat during 24 hours after surgery was 8% in Dexamethasone group and 22% in distilled water group. The intensity of pain at the intended times after surgery significantly decreased in both groups (P=0.019). The prevalence of coughing showed a significant decrease at 1 h after surgery in both groups (P=0.025). The local application of Dexamethasone on the LMA cuff was effective on reducing the prevalence and acuity of sore throat after surgery. Regarding lack of any complications due to the use of Dexamethasone, it can be used to prevent the postoperative sore throat."