Aishwarya S. Patil and SV Pimpale
India is very traditional country and we are lucky to have treasure house of traditional medicine. Now a day’s Ayurveda medicine has been a boon in the treatment of much disastrous disease. Rheumatoid arthritis is one of the autoimmune disorders which are due to faulty metabolism of body and stress. It becomes chronic inflammatory disorder which results in severe pain. Allopathic medicine can reduce pain but the root cause remains untreated. In this paper we study on combination of most potent herbal drugs like Ashwagandha, safe musli, mahayogiraj googol and maharasandi swath that have clinically proven antiinfflamatory, analgesic and anti-arthritic activities when used alone. Now a day’s such kind of inflammatory disorders increases day by day due to change in lifestyle. Inflammation in any part of the body result either due to physical injury or due to internal faulty metabolism of the body. Faulty metabolism of the body may be due to improper diet, irregular food timings, anger, and stress. As per Ayurveda, faulty metabolism of body produces Aam (toxins or Reactive Oxygen Species). These Aam or Reactive Oxygen Species (ROS) are highly unstable compounds and are key signaling molecules that play an important role in the progression of inflammatory disorders. As per Ayurveda ROS leads to imbalance in the three main pillars of the body that is vata-pittakapha. Under normal conditions, ROS levels are controlled by the body’s complex antioxidant defense system and there is equilibrium between ROS formation and degradation. Overproduction of ROS and/or inadequate antioxidant defense disturbs this equilibrium in favor of ROS upsurge that results in oxidative stress. A deficiency in the body’s natural antioxidant defense mechanisms has been implicated as the etiological or pathological factor in several clinical disorders.